Alzheimer's Research & Therapy

Articles

		Volume 1 Issue 2
		Review
		Review Proteinopathy-induced neuronal senescence: a hypothesis for brain failure in Alzheimer's and other neurodegenerative diseases Todd E Golde, Victor M Miller Alzheimer's Research & Therapy 2009, 1:5 (12 October 2009) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Golde and Miller propose an integrative hypothesis that provides new insights into how a variety of misfolded protein aggregates can result in neurodegeneration.
		Review Cerebral amyloid angiopathy in the aetiology and immunotherapy of Alzheimer disease Roy O Weller, Stephen D Preston, Malavika Subash, Roxana O Carare Alzheimer's Research & Therapy 2009, 1:6 (12 October 2009) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Weller et al. highlight the importance of addressing neuro-immune interactions when devising therapeutic strategies for Alzheimer's disease.
		Research
		Research Persistent treatment with cholinesterase inhibitors and/or memantine slows clinical progression of Alzheimer disease Susan D Rountree, Wenyaw Chan, Valory N Pavlik, Eveleen J Darby, Samina Siddiqui, Rachelle S Doody Alzheimer's Research & Therapy 2009, 1:7 (21 October 2009) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Persistent treatment with cholinesterase inhibitors and/or memantine had a positive impact on Alzheimers disease (AD) progression by multiple cognitive and functional outcome measures.