Table 4

Logistic regression model illustrating the odds of all-cause dementia (95% confidence intervals) by combinations of stroke and APOE genotype

n

Basic adjusted models*

Fully adjusted models†

Stroke - APOE ε4 -

388

Reference

Reference

Stroke + APOE ε4 -

219

2.2 (1.2-4.0)

2.2 (1.1-4.2)

Stroke - APOE ε4 +

151

1.4 (0.8-2.4)

1.3 (0.7-2.5)

Stroke + APOE ε4 +

84

14.8 (6.3-34.9)

14.9 (5.8-38.0)

P for stroke × APOE ε4 interaction = 0.001†

Population weights are used to adjust for the sampling design. *Adjusted for age, sex, education, ethnicity, and Health and Retirement Study (HRS) wave. †Adjusted for age, sex, education, ethnicity, HRS wave, heart disease, hypertension, and diabetes. APOE ε4, apolipoprotein ε4.

Llewellyn et al. Alzheimer's Research & Therapy 2010 2:19   doi:10.1186/alzrt43