Table 1 |
||||
|
Different herbs and formulations effective in the treatment of Alzheimer's disease |
||||
|
Product |
Composition |
Design |
Outcome measure |
Source |
|
|
||||
|
Huperzine A |
An extract from Lycopodium |
A 12-week randomized, double-blind, placebo-controlled trial |
ADAS-cog, MMSE, CIBIC-plus, ADL of patients with mild to moderate AD |
Zhang and colleagues [7] |
|
Gingko Biloba |
EGb 761 |
A 24-week randomized, placebo- controlled, double-blind study |
MMSE and CGI in patients with mild to moderate AD |
Mazza and colleagues [4] |
|
Panax ginseng |
Ginsenosides |
A 12-week open-label, randomized double-blind, placebo-controlled study |
ADAS and MMSE scores of AD patients |
Lee and colleagues [17] |
|
Salvia officinalis |
Leaf extract containing monoterpene, flavonoids, polyphenol |
A 4-month, parallel-group, placebo- controlled trial |
ADAS-cog and CDR in patients with mild to moderate AD |
Akhondzadeh and colleagues [11] |
|
Ba Wei Di Hunag Wan |
Powder of Rehmannia with another seven plants mixed with honey |
An 8-week randomized, double-blind, placebo-controlled trial |
MMSE and Barthel Index scores in patients with mild to severe dementia |
Iwasaki and colleagues [15] |
|
Yi-Gan San formula |
A mixture of seven different rootstock and branches, lyophilized dry extract |
A 4-week randomized, observer-blind, controlled trial |
NPI and ADL in patients with mild to severe dementia |
Iwasaki and colleagues [16] |
|
|
||||
|
AD, Alzheimer disease; ADAS-cog, Alzheimer disease assessment scale-cognitive subscale; ADL, activities of daily living; CDR, Clinical Dementia Rating; CGI, Clinical Global Impression; CIBIC-plus, Clinician's Interview-Based Impression of Change plus Caregiver Input; MMSE, mini-mental state examination; NPI, neuropsychiatric Inventory. |
||||
|
Tian et al. Alzheimer's Research & Therapy 2010 2:30 doi:10.1186/alzrt54 |
||||