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Volume 3 Issue 6

Comment

Commentary   Free

Predicting Alzheimer's risk: why and how?

Deborah E Barnes, Sei J Lee Alzheimer's Research & Therapy 2011, 3:33 (25 November 2011)

Abstract | Full text | PDF | PubMed |  Editor’s summary

In light of recent research, Barnes and Lee consider the current limitations and future directions in identifying individuals at increased risk of developing symptomatic Alzheimer's disease (AD).

Review

Review   Free Highly Accessed

Amyloid imaging in the differential diagnosis of dementia: review and potential clinical applications

Robert Laforce, Gil D Rabinovici Alzheimer's Research & Therapy 2011, 3:31 (10 November 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Potential clinical applications of amyloid positron emission tomography (PET) and its role in the differential diagnosis of a range of neurodegenerative conditions are reviewed by Laforce and Rabinovici.

Review   Free Highly Accessed

Molecular imaging in Alzheimer's disease: new perspectives on biomarkers for early diagnosis and drug development

Agneta Nordberg Alzheimer's Research & Therapy 2011, 3:34 (2 December 2011)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Nordberg reviews recent progress in molecular imaging and functional biomarkers, which can provide valuable information for early Alzheimer's disease (AD) detection, assessing disease progression, and the development of new therapeutics.

Review   Free

Patient self-report for evaluating mild cognitive impairment and prodromal Alzheimer's disease

Lori Frank, William R Lenderking, Kellee Howard, Marc Cantillon Alzheimer's Research & Therapy 2011, 3:35 (9 December 2011)

Abstract | Full text | PDF | PubMed |  Editor’s summary

The uses of, and issues associated with, patient-reported outcome measures in mild cognitive impairment and prodromal Alzheimer's disease are discussed by Frank and colleagues.

Report

Meeting report   Free

Beyond amyloid: a diverse portfolio of novel drug discovery programs for Alzheimer's disease and related dementias

Rachel F Lane, Diana W Shineman, Howard M Fillit Alzheimer's Research & Therapy 2011, 3:36 (20 December 2011)

Abstract | Full text | PDF | PubMed

Research

Research   Open Access

A web-based normative calculator for the uniform data set (UDS) neuropsychological test battery

Steven D Shirk, Meghan B Mitchell, Lynn W Shaughnessy, Janet C Sherman, Joseph J Locascio, Sandra Weintraub, Alireza Atri Alzheimer's Research & Therapy 2011, 3:32 (11 November 2011)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Uniform Data Set clinical researchers are provided with a new online interactive calculator that provides a normative score to help evaluate neuropsychological test performance in subjects with Alzheimer's disease.


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