Review

Apolipoprotein E, amyloid-ß clearance and therapeutic opportunities in Alzheimer's disease

Adam Kline

Alzheimer's Research & Therapy 2012, 4:32 (27 August 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Adam Kline discusses therapeutic approaches targeting apolipoprotein E (apoE), the most significant risk factor for non-familial Alzheimer's disease (AD), including key interactions of apoE and amyloid-beta pathology and preclinical animal models.

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