Alzheimer's disease risk alleles in TREM2 illuminate innate immunity in Alzheimer's disease

Todd E Golde , Wolfgang J Streit and Paramita Chakrabarty

Alzheimer's Research & Therapy 2013, 5:24 (21 May 2013)

Golde and colleagues review the function of innate immune signalling in Alzheimer's disease (AD) following recent studies showing variants of TREM2, a triggering receptor on myeloid cells, is significantly associated with AD risk.

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