Review

Evidence for impaired amyloid β clearance in Alzheimer's disease

Kristin R Wildsmith , Monica Holley , Julie C Savage , Rebecca Skerrett and Gary E Landreth

Alzheimer's Research & Therapy 2013, 5:33 (12 July 2013)

Landreth and colleagues review evidence indicating that increasing levels of apolipoprotein E enhances the clearance of amyloid beta (Aβ) in the brain and is a potential therapeutic strategy in Alzheimer's disease (AD).

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